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differential types vasculitis algorithm glomerulonephritis cryoglobulins monoclonal nephritis oncology paraproteinemias progressive rapidly renal vasculitides
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... , Cryoglobulinemia ... #differential #diagnosis ... #algorithm #rheumatology
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... #Classification ... #Algorithm #diagnosis ... differential #types #rheumatology ... #nephrology #renal
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
IgA nephropathy, lupus ... nephritis, cryoglobulinemia ... post-infectious GN ... #Classification ... #Nephrology
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Cryoglobulinemia ... Classification ... Liver, kidney (MPGN ... #Types #hematology ... #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
& Cryoglobulinemic ... WM: Vasculitis (Cryoglobulinemic ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... (e.g. systemic lupus ... Cryoglobulins #diagnosis ... #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... ANCA +MPO) • Cryoglobulinemic ... such as systemic lupus ... #rheumatology # ... classification
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