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differential glomerulonephritis algorithm classification glomerular management associated causes comparison cryoglobulinemia cryoglobulinemic diseases erythematosus involvement microscopy pathology progressive proteinuria rapidly sle
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Microscopy (EM) Haematuria ... /nephritis • Lupus ... • Amyloid RPGN ... glomerular #diseases #nephrology ... comparison #table #diagnosis
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary CLINICAL • Nephritic syndrome (Casts) • Marked proteinuria (may be
CLINICAL • Nephritic ... • Often severe renal ... Leukocyturia • Vasculitic ... GlomeruloNephritis #nephrology ... #GN
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Diagnosis Framework ... urine • 1ml blood ... of GN or vasculitis ... causes #urology #nephrology ... blood
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
glomerular disease (hematuria ... IgA nephropathy, lupus ... nephritis, cryoglobulinemia ... post-infectious GN ... #Nephrology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
Renal involvement ... presentation • Hematuria ... • Tendency for nephrotic ... #Management #Rheumatology ... Cryoglobulinemic #Nephrology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... proteinuria, hematuria ... APLA/LAC: • Renal ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
multiplex • Hematuria ... rapidly progressing GN ... pulmonary and renal ... Large Vessel: Blood ... #rheumatology #
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
basement membrane; GN ... atypical HUS; MPGN ... content [85].2>5 red blood ... Hematuria may be ... #syndrome #nephrology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Mononeuritis multiplex • Hematuria ... pulmonary and renal ... pulses, bruits, or blood ... #Rheumatology
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