11 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Erythematosus ... Lupusreference #Renal #diseases ... venn #nephrology #nephritis ... #classification ... #types #rheumatology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
conjunctivitis Type ... Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Erythematosus, ... #Types #Classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... Non-autoimmune rheumatologic ... • Type-I Interferonopathies ... (nephrotic-range ... #Diagnosis #Rheumatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
during hemolytic disease ... , and systemic lupus ... erythematosus ... #Classification ... Diagnosis #Reactions #Table
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... - systemic lupus ... erythematosus ... purpura-arthralgia-nephritis ... Vessels #Diagnosis #Rheumatology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... erythematosus Type ... #allergy #table ... #classification
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... IgA nephropathy, lupus ... nephritis, cryoglobulinemia ... post-infectious GN ... autoAb against type
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... nephritis. ... #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... (e.g. systemic lupus ... erythematosus ( ... #classification ... #rheumatology #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Erythematosus ( ... nephritis, NPSLE ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #