785 results
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... Worsening macrocytic anemia ... wt loss • If anemia ... parasthesias, gait ... B12 #Cobalamin #Deficiency
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
hypothyroidism • Zinc deficiency ... • Vitamin C deficiency ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait
Criss-Cross Gait on Physical Exam 

Seen in Glucose Transporter type 1 Deficiency Syndrome

#CrissCross #Criss #Cross #Gait
Criss-Cross Gait ... Transporter type 1 Deficiency ... #Criss #Cross #Gait ... neurology #GLUT1 #deficiency
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... B12 or Folate deficiency ... Cell RBC: G6PD deficiency ... elliptocytosis, Severe iron deficiency
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... anemia, Thalassemia ... Thalassemia, Iron-deficiency ... Post-splenectomy, Vitamin E deficiency ... cells - G-6-PD deficiency
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... Algorithm - Iron deficiency ... anemia - Anemia ... inflammation - Anemia ... and/or folate deficiency
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
Iron Deficiency ... Anemia vs Anemia ... TIBC-specific for iron deficiency ... Bloodman #Iron #Deficiency ... #Anemia #Chronic
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach to Anemia ... inflammation) • Iron deficiency ... Sideroblastic anemia ... Megaloblastic: Folate deficiency ... , B12 deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80 fL) • Iron Deficiency ... Poisoning • Anemia ... 100 fL) • B12 Deficiency ... • Folate Deficiency
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
Syndrome - Thiamine Deficiency ... thiamine (vitamin B1) deficiency ... ataxia (broad-based gait ... and retrograde amnesia ... #B1 #thiamine #deficiency