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diagnosis differential algorithm hematology pathophysiology management peds secondary cardiology dermatology neurology classification geriatrics iron signs symptoms systemic thiamine vitaminb12 b1
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
dysfunction (e.g. gait ... upper limb) • Nutritional ... risk factor for nutritional ... development of Korsakoff syndrome ... Management #neurology #nutrition
Causes of Pediatric Diarrhea - Differential Diagnosis Algorithm Infectious: • Viral • Bacterial • Parasitic Malabsorption: • Lactase
Causes of Pediatric ... • Short Bowel Syndrome ... Irritable Bowel Syndrome ... Diagnosis #Algorithm #Causes ... #Peds #Pediatrics
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... diarrhoea, Short bowel syndrome ... /jejunal nutrition ... Haematological: Anaemia ... drkeithsiau #Copper #Deficiency
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... drkeithsiau #Iron #Deficiency ... #Causes #differential ... #diagnosis #anemia ... #nutrition
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... Diagnosis #Algorithm #Causes
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... cancer) #Iron #Deficiency ... differential #diagnosis #causes ... #nutrition
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
• Thiamine - Nausea ... oculomotor dysfunction, gait ... ataxia), Korsakoff syndrome ... B12 - Macrocytic anemia ... Bypass #vitamin #nutrition
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... E - Haemolytic anaemia ... Wernicke-Korsakoff syndrome ... #Vitamins #Deficiency ... signs #symptoms #nutrition
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron deficiency ... Megaloblastic: Vitamin B12 deficiency ... , Folate deficiency ... Myelodysplastic syndrome ... differential #diagnosis #causes
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... B12 • Folate deficiency
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