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diagnosis differential neurology treatment signs symptoms hematology nutrition endocrinology pharmacology sideeffects algorithm barre cardiology disorders encephalopathy guillain hemophagocytic hlh inhibitors
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Vomiting Serotonin Syndrome ... Dysfunction, Weight gain ... Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
B1 (Thiamine) Deficiency ... Diagnosis and Management ... dysfunction (e.g. gait ... development of Korsakoff syndrome ... #Diagnosis #Management
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
• Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... Systemic effect -> Nausea ... pruritus, weight gain ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
SSRI Initiation How long before increasing dose? • 4 wks. Initial response in 2-4 wks, max response
transient Gl upset (nausea ... cross-titration need to wait ... Paroxetine: Weight gain ... Initiation #depression #psychiatry ... #treatment #management
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... → Inflammation causes ... endpoint of all-cause ... heartfailure #diagnosis #management
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts caused ... changes and may cause ... Hypo-Mg2+ • Vitamin deficiency ... • Vitamin D deficiency ... Differential #Diagnosis #Pathophysiology
Weight Gain / Obesity - Differential Diagnosis Algorithm Decreased Expenditure: • Sedentary Lifestyle • Smoking Cessation
Weight Gain / Obesity ... Polycystic Ovarian Syndrome ... • Cushing's Syndrome ... Hypogonadism • GH Deficiency ... endocrinology #causes
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
although hepatic causes ... namely, the many causes ... rare): - Reye syndrome ... Primary carnitine deficiency ... #Ammonia #Pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Carpal Tunnel Syndrome ... tolerance • Weight gain ... endocrinology #pathophysiology
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