11 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... Alopecia, oral ulcers ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
thrombophlebitis, pyoderma gangrenosum ... lesions, pyoderma gangrenosum ... response to local skin ... Arthritis, AS Treatment ... #diagnosis #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... Skin manifestations ... #Syndrome #Treatment ... #management #pharmacology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... Alopecia, oral ulcers ... Usual therapeutic management ... Evolution: Chronic disease
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Causes: - Idiopathic ... DDX: - Pyoderma gangrenosum ... - Lupus - Leukemia ... Treatment: - Systemic
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... effusion), mouth (ulcers ... nose (epistaxis), skin ... vesicular rash, ... Nephrocalcinosis causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... livedo reticularis, ulcers ... mucositis - Rash ... genital aphthous ulcers ... such as systemic lupus
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Edema in 70% of cases ... Skin involvement ... : symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
responsible for most cases ... weight loss • Skin ... : Rash is the most ... Albuminuria, nephrotic syndrome ... stages #diagnosis #management
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
24%) • Mouth ulcers ... sweats (28%) • Skin ... rash (48%) • ... antibody test) Treatment ... ART to slow HIV disease