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Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from

four patterns: ... and what kind of pattern ... the most common pattern ... The cystic pattern ... pattern on a CXR

Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
• Homogeneous pattern:
-

and Cytoplasmic Patterns ... Nuclear Patterns ... • Homogeneous pattern ... : • Reticular/ ... SLE, SjS, CTD-ILD

Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic

Nodular pattern ... Hypersensitivity pneumonitis: ill ... Clinical #Radiology #HRCT ... #CTChest #Nodular ... #Pattern #Comparison

The CXR demonstrates a reticular interstitial pattern with a preference at the lung bases.
The HRCT demonstrates

demonstrates a reticular ... interstitial pattern ... The HRCT demonstrates ... Radiology #CXR #UIP #CTChest ... #Pattern #Honeycombing

Perilymphatic distribution
Perilymphatic nodules are most commonly seen in sarcoidosis.
They also occur in silicosis, coal-worker's pneumoconiosis and

thickening in the reticular ... pattern. ... Radiology #Pulmonary #HRCT ... #CTChest #Perilymphatic

Here are the most common examples of these four patterns on a chest x-ray (click image

of these four patterns ... on a chest x-ray ... consolidation - Multifocal ill-defined ... Interstitial - Reticular ... Consolidation #Patterns

Algorithm for nodular pattern
The algorithm to distinguish perilymphatic, random and centrilobular nodules is the following:
- Look

pattern The algorithm ... are visible, the pattern ... Radiology #Pulmonary #HRCT ... #CTChest #NodularPattern ... #Nodular #Pattern

The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-

The fourth pattern ... low attenuation pattern ... on the basis of HRCT ... Radiology #Pulmonary #CTChest

Chronic hypersensitivity pneumonitis
The key findings in chronic hypersensitivity pneumonitis are:
Mosaic pattern with areas of ground-glass atenuation

pneumonitis are: Mosaic pattern ... The HRCT shows a ... mosaic pattern ... and intralobular reticular ... Radiology #CXR #CTChest

Lymphangitis carcinomatosis also produces a reticular pattern.
It is best appreciated on HRCT-images. #Clinical #Radiology #CTChest #Lymphangitic

also produces a reticular ... pattern. ... appreciated on HRCT-images ... Clinical #Radiology #CTChest

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