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diagnosis hematology oncology syndrome classification criticalcare myelodysplastic neurology overview shock differentiation encephalopathy gravis hemophilia myasthenia myelodysplasia posterior pres syndromes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... risk-stratification • Risks: infection ... transformation to acute ... only curative treatment ... #treatment #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... #diagnosis #management ... #hematology #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Differential ... syndrome, ADEM, Acute ... the underlying cause ... • Treatment of ... Syndrome #diagnosis #management
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... - Acute Bleeding ... Avoid meds that ... #treatment #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... aspiration and acute ... precipitated by: Drugs, infection ... immunosuppressants - Meds ... Gravis #diagnosis #management
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
While initially reversible ... Inflammatory: infectious ... anaphylaxis, toxins/meds ... #criticalcare #differential ... #causes #classification
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
While initially reversible ... Inflammatory: infectious ... anaphylaxis, toxins/meds ... #criticalcare #differential ... #causes #classification
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... • Parvovirus infection ... factor (GCSF) treatments ... blood count with differential ... Syndromes #diagnosis #hematology
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