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diagnosis hematology oncology mds neurology algorithm anemia aplastic apml dermatology differentiation encephalopathy gravis infancy infant myasthenia myelodysplasia nonpalpable palpable pediatrics
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... risk-stratification • Risks: infection ... transformation to acute ... #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Thrombocytosis): • Acute ... infection • Solid ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... petechiae) • Frequent infections ... • Parvovirus infection ... blood count with differential ... #hematology #oncology
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm Congenital Anomaly / Disorder: •
Causes of Sudden ... Infancy (SUDI) - Differential ... Accidental* Other: • Acute ... Sudden Infant Death Syndrome ... #Peds #Pediatrics
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - APLS • Acute ... Infectious Purpura ... pneumoniae Vascular Fragility ... #rheumatology #
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... aspiration and acute ... precipitated by: Drugs, infection ... immunosuppressants - Meds ... Gravis #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Idiopathic • Infections ... • Hypocellular myelodysplastic ... aplastic anemia Treatment ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... APML #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Reversible course Differential ... , ADEM, Acute toxic ... the underlying cause ... • Treatment of ... #diagnosis #management
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