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Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
kidney injury (AKI ... vascular supply; glomerular ... and interstitial disease ... GBM, Glomerular ... #Kidney #Injury
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... • Vascular • Glomerular ... Immune-complex disease ... Bilateral ureteral disease ... #Kidney #Injury
Kidney Syndromes - A Guide to Compartmentalize the Etiologies of Kidney Disease
1) Tubule and interstitium
2) Vasculature
3)
Kidney Syndromes ... Etiologies of Kidney ... Disease 1) Tubule ... Vasculature 3) Glomerulus ... Causes #Failure #Injury
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... Kidney Injury - ... Tubules (ATN) • Glomerular ... CMC_IM #AKI #Acute
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease ... #Kidney #Injury
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
tubular cells - Acute ... tubular injury ... red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... Diagnostic of glomerular
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
Acute Kidney Injury ... damage to the glomeruli ... dye) • AIN (acute ... Cellular debris • Kidney ... #Kidney #Injury
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Injury • Pre-Renal ... therapy • Osmotic injury ... Vitamin C • Glomerular ... Disease: Drug induced
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... INTRINSIC: - Glomerular ... appropriate) #Acute ... #Kidney #Injury
Extrapulmonary manifestations of COVID-19
 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke
 • Renal:
Stroke • Renal: Acute ... kidney injury, ... vein thrombosis, Pulmonary ... cor pulmonale ... Extrapulmonary #Diagnosis #Signs