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differential nephrology kidney syndromes algorithm atlas blood diseases glomerulonephritis key management membranoproliferative microscopy mpgn nephritic proteinuria prs pulmonary rheumatology treatment
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... diabetes)) #Glomerular ... #Diseases #Nephritic
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... glomerular disease ... • Hyaline casts ... renal disease
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... • Signs of glomerular ... RBC casts → Diagnostic ... disease Renal
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Calculi Glomerular ... RBCs and/or RBC casts ... epithelial side of glomerular ... endothelial side of glomerular
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - TTP/HUS • Glomerular ... necrosis (causes ... nephritis (AIN) ... #Injury #Classification
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Acute Kidney Injury ... INTRINSIC: - Glomerular ... white blood cell casts ... tubular cell casts ... or pigmented casts
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... formation along glomerular ... (Dense deposit disease ... #renal
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
: (AKI, proteinuria ... injury), Coags ... Goodpasture's cause ... , RBC casts, low ... hypercellular glomeruli
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
multiplex • Hematuria ... tract, and often causes ... Vasculitis - Skin, glomeruli ... : - Kidneys: glomerular ... purpura: strong sign
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