14 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephrotic Syndromes ... diabetes)) #Glomerular ... #Diseases #Nephritic ... #Nephrotic #Syndromes
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Thin GBM disease ... • Hereditary nephritis ... • Pauci-immune disease ... and >3.5g/day (nephrotic
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Intrinsic renovascular disease ... - TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease ... Acute interstitial nephritis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... basement membrane disease ... • Signs of glomerular ... disease Renal
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... - Glomerular - ... - Interstitial nephritis ... necrosis, Sickle cell disease ... #Diagnosis #Causes
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... immune deposits in glomeruli ... nephropathy, lupus nephritis ... post-infectious GN Anti-Glomerular
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
impairment), heart disease ... cluster, the diseases ... clusters because nephritic ... #diagnosis #glomerular ... #proteinuria #nephrotic
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Skin, glomeruli ... : - Kidneys: glomerular ... (Granulomatous disease ... rheumatic diseases ... differential #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
peritonitis Lupus nephritis ... abnormalities (non-nephrotic ... ) • Frank nephritis ... (nephrotic-range ... suspicion for nephritis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
causes differentiated ... Post-strep GN, Lupus Nephritis ... involvement: Anti-GBM Disease ... #differential # ... #rheumatology