26 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... diabetes)) #Glomerular ... #Diseases #Nephritic
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
/nephritic syndromes ... the patient have glomerular ... casts or dysmorphic ... RBCs in urine)? ... #Diagnosis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
basement membrane disease ... • Signs of glomerular ... RBC castsDiagnostic ... disease Renal ... #nephrology #renal
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... glomerular disease ... renal disease ... #nephrology #casts
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Calculi Glomerular ... RBCs and/or RBC casts ... • Thin GBM disease ... • Pauci-immune disease
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
kidney injury (AKI ... Renal causes of ... vascular supply; glomerular ... and interstitial disease ... GBM, Glomerular
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... Renal: - Glomerular ... membrane, Alport syndrome ... necrosis, Sickle cell disease ... #Diagnosis #Causes
Kidney Syndromes - A Guide to Compartmentalize the Etiologies of Kidney Disease
1) Tubule and interstitium
2) Vasculature
3)
Kidney Syndromes ... Disease 1) Tubule ... Vasculature 3) Glomerulus ... #Kidney #Syndromes ... #Injury #AKI
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - TTP/HUS • Glomerular ... disease - Post-infectious ... #Injury #Classification ... #diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
) - Loss of kidney ... with evidence of glomerular ... disease (hematuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular