15 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... Nephrotic Syndromes ... Nephritic syndrome ... Nephrotic syndrome ... glomerulonephritis #Glomerular
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... #Nephrotic #Syndromes
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Syndrome Step ... /nephritic syndromes ... the patient have glomerular ... casts or dysmorphic ... #Syndrome #Comparison
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Alport syndrome ... syndrome: • ... • Signs of glomerular ... RBC casts → Diagnostic ... • Nutcracker syndrome
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Calculi Glomerular ... RBCs and/or RBC casts ... epithelial side of glomerular ... endothelial side of glomerular
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... Diagnostic of glomerular ... renal disease ... #casts
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... a.k.a. cardiorenal syndrome ... a.k.a. hepatorenal syndrome ... - TTP/HUS • Glomerular ... necrosis (causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... Cytomegalovirus; GBM = glomerular ... hemolytic-uremic syndrome ... cell/white cell casts ... #syndrome #nephrology
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... Differential Diagnosis Renal ... : - Glomerular ... membrane, Alport syndrome ... - Interstitial nephritis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... formation along glomerular ... anti-phospholipid syndrome ... #diagnosis #renal