11 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... - Berger disease ... Minimal change disease ... #Glomerular ... #Diseases #Nephritic
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... diabetes)) #Glomerular ... #Diseases #Nephritic
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
RBCs and/or RBC casts ... • Thin GBM disease ... • Hereditary nephritis ... • Pauci-immune disease ... and >3.5g/day (nephrotic
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease ... interstitial nephritis
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... disease, but can ... Diagnostic of glomerular ... disease • Leukocytes
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... Disease Associations ... Advanced kidney disease ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
cell/white cell casts ... impairment), heart disease ... diagnosis cluster, the diseases ... clusters because nephritic ... #proteinuria #nephrotic
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... chronic kidney diseases ... suggestive of nephrotic ... suggestive of glomerulonephritis ... #nephrology #interpretation
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... formation along glomerular ... (Dense deposit disease ... glomerulopathy, radiation nephritis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... basement membrane disease ... : - RBC casts ... disease Renal