11 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... diabetes)) #Glomerular ... #Diseases #Nephritic ... #Proteinuria #Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... /nephritic syndromes ... the patient have glomerular ... casts or dysmorphic ... #Nephritic #Nephrotic
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
RBCs and/or RBC casts ... • Thin GBM disease ... • Hereditary nephritis ... • Pauci-immune disease ... and >3.5g/day (nephrotic
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
cell/white cell casts ... impairment), heart disease ... diagnosis cluster, the diseases ... clusters because nephritic ... #proteinuria #nephrotic
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
of Glomerular Bleeding ... basement membrane disease ... • Signs of glomerular ... RBC casts → Diagnostic ... disease Renal
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Intrinsic renovascular disease ... - TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease ... Acute interstitial nephritis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
- AKI Workup Algorithm ... clinical context and signs ... • Interstitial nephritis ... #AKI #Workup #Algorithm ... Differential #Diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... , +/- proteinuria ... formation along glomerular ... (Dense deposit disease ... glomerulopathy, radiation nephritis
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disease 24- ... of glomerular disease ... glomerulonephritis #nephrotic ... #nephritic #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disease 1) 24- ... of glomerular disease ... #glomerular #disease ... #nephrotic #nephritis