15 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... diabetes)) #Glomerular ... #Diseases #Nephritic ... #Proteinuria #Nephrology
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Diseases Nephrotic ... formation #Glomerular ... #Diseases #differential ... spectrum #diagnosis #nephrology
Intrinsic Renal Disease - Differential Diagnosis
Vascular:
 • Macrovascular: Renal artery occlusion, Fibromuscular disease
 • Microvascular: TTP/HUS,
Intrinsic Renal Disease ... HTN, Vasculitis Glomerular ... : • Nephrotic: ... Amyloidosis, MPGN • Nephritic ... #nephrology #differential
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
RBCs and/or RBC casts ... • Thin GBM disease ... • Hereditary nephritis ... • Pauci-immune disease ... and >3.5g/day (nephrotic
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... disease, but can ... Diagnostic of glomerular ... key #diagnosis #nephrology
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
- TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease ... Acute interstitial nephritis ... #diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... immune deposits in glomeruli ... nephropathy, lupus nephritis ... Diagnosis #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
cell/white cell casts ... impairment), heart disease ... clusters because nephritic ... #proteinuria #nephrotic ... #syndrome #nephrology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
treat underlying cause ... CHF, cirrhosis, nephrotic ... Pulmonary Diseases ... , CNS Disease, Meds ... Algorithm #diagnosis #nephrology
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Diagnosis Renal: - Glomerular ... - Interstitial nephritis ... - PKD, Medullary ... necrosis, Sickle cell disease ... #urology