10 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... • Causes of Glomerular ... basement membrane disease ... • Signs of glomerular ... disease Renal
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Diagnosis Renal: ... - Glomerular - ... - Interstitial nephritis ... necrosis, Sickle cell disease ... #Hematuria #Differential
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Injury • Pre-Renal ... Vitamin C • Glomerular ... Disease: Drug induced ... vasculitis, TMA
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Rapidly Progressive ... with evidence of glomerular ... disease (hematuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Diagnosis for Pulmonary ... , Behcet disease ... sclerosis • Anti-Glomerular ... Goodpasture's Disease
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Skin, glomeruli ... disease, and ocular ... : glomerular ischemia ... rheumatic diseases ... differential #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... • Limited to Kidney ... involvement: Anti-GBM Disease ... #differential # ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... life-threatening diseases ... Inflammatory eye disease ... injury), Coags ... hypercellular glomeruli
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... rheumatic diseases ... atherosclerotic disease ... : Non-glomerular ... #Differential #Diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease ... disease common