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nephrology algorithm causes classification renal rheumatology glomerulonephritis rpgn urology acute aki blood druginduced management medications progressive prs rapidly syndrome syndromes
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
• Calculi Glomerular ... epithelial side of glomerular ... • Thin GBM disease ... endothelial side of glomerular ... • Pauci-immune disease
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Drug Induced Kidney ... Vitamin C • Glomerular ... Disease: Drug induced ... vasculitis, TMA ... #differential #
Causes of Hematuria - Differential Diagnosis Renal: - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
- Glomerular - ... - Interstitial nephritis ... Medullary sponge kidney ... necrosis, Sickle cell disease ... #Hematuria #Differential
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
) - Loss of kidney ... with evidence of glomerular ... disease (hematuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... • Causes of Glomerular ... basement membrane disease ... • Signs of glomerular ... disease Renal
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... Intrinsic renovascular disease ... - TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... Diagnosis for Pulmonary ... , Behcet disease ... sclerosis • Anti-Glomerular ... Goodpasture's Disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Skin, glomeruli ... disease, and ocular ... : glomerular ischemia ... rheumatic diseases ... differential #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... life-threatening diseases ... Inflammatory eye disease ... quantify renal injury ... hypercellular glomeruli
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... • Limited to Kidney ... involvement: Anti-GBM Disease ... #differential # ... diagnosis #algorithm
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