13 results
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
• Calculi Glomerular ... epithelial side of glomerular ... • Thin GBM disease ... endothelial side of glomerular ... • Pauci-immune disease
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Vitamin C • Glomerular ... Disease: Drug induced ... vasculitis, TMA ... #differential #
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
- Glomerular - ... - Interstitial nephritis ... Medullary sponge kidney ... necrosis, Sickle cell disease ... #Hematuria #Differential
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
) - Loss of kidney ... with evidence of glomerular ... disease (hematuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... • Causes of Glomerular ... basement membrane disease ... • Signs of glomerular ... disease Renal
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... Intrinsic renovascular disease ... - TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... Diagnosis for Pulmonary ... , Behcet disease ... sclerosis • Anti-Glomerular ... Goodpasture's Disease
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Skin, glomeruli ... disease, and ocular ... : glomerular ischemia ... rheumatic diseases ... differential #diagnosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... quantify renal injury ... hypercellular glomeruli ... #diagnosis #management
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... • Limited to Kidney ... involvement: Anti-GBM Disease ... #differential # ... diagnosis #algorithm