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diagnosis neurology rheumatology nephrology pulmonary syndrome treatment amyotrophic ankylosingspondylitis blood causes cerebritis classification cns complications erythematosus extraarticular hematuria lateral manifestations
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... ANCA-positive vasculitis ... Complex: Systemic lupus ... sclerosis • Anti-Glomerular ... #Syndrome #differential
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... • Causes of Glomerular ... of glomerular hematuria ... Suggestive of glomerular ... disease Renal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... - Skin, glomeruli ... : - Kidneys: glomerular ... disease Differential ... purpura: strong sign
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Meningitis, Myelopathy, Encephalopathy ... Cerebrovascular Disease ... , PRES Pathophysiology ... (for secondary APS ... cerebritis #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... pulmonary and renal ... purpura: Strong sign ... • Kidneys: Non-glomerular ... disease #Vasculitis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... life-threatening diseases ... Inflammatory eye disease ... hypercellular glomeruli ... #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Presentation: - Disease ... course of the disease ... conditions listed in differential ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... Immunosuppressive agents, Renal ... Etiology: • Pathophysiology ... Reversible course Differential ... Syndrome #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... - Sjogren - Vasculitis ... Myelitis #diagnosis #management ... #neurology #differential
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Inflammatory Bowel Disease ... abnormalities • Renal ... amyloid proteins in glomeruli ... Complications #pathophysiology ... #diagnosis #signs
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