25 results
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis of Alcoholic ... or 60 (male) g alcohol ... I antitrypsin deficiency ... Presence of atypical laboratory ... Hepatitis #AH #hepatology
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate Deficiency ... • Alcohol - Alcohol ... Alcoholics have ... Alcoholics have ... differential #diagnosis #hematology
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
Interpretation Iron deficiency ... Ferritin Iron deficiency ... Interpretation #deficiency ... #differential #hematology ... #laboratory
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
• Vitamin K deficiency ... • Factor VII deficiency ... II, fibrinogen deficiency ... Thromboplastin #laboratory ... #hematology #diagnosis
Non-invasive biomarkers for excessive alcohol use
Acute Alcohol Use Biomarkers:
 - Ethanol
 - Ethyl Glucuronide (EtG) and
for excessive alcohol ... use Acute Alcohol ... (EtS) Chronic Alcohol ... - Carbohydrate deficient ... dependence #abuse #laboratory
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
• 812, Folate Deficiency ... Liver Disease • Alcohol ... diagnosis #algorithm #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... tumors, Acute alcoholism ... Acanthocytes - Alcohol ... cells - G-6-PD deficiency ... #differential #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• NAFLD • Alcohol ... • AIH • A1AT deficiency ... Ducts • PSC • Alcoholic ... Others #LFTs #Hepatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Diseases: • GATA2 deficiency ... Deficiencies: • Alcohol ... B12 • Folate deficiency ... Differential #Diagnosis #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
inflammation) • Iron deficiency ... Megaloblastic: Folate deficiency ... , B12 deficiency ... Liver disease, Alcoholism ... Differential #Diagnosis #hematology