15 results
Gowers' Sign on Physical Exam

Seen in this patient with Duchenne muscular dystrophy (DMD)

#Gowers #Sign #PhysicalExam #neurology
Gowers' Sign on ... this patient with Duchenne ... muscular dystrophy (DMD ... ) #Gowers #Sign ... #Duchenne
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
HHS) Absolute Insulin ... deficit: - Type I DM ... : No insulin produced ... - Type II DM ... pathophysiology #comparison #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Summary Table Insulin ... comparison #management #endocrinology ... #dm2
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
140-180 mg/dL Insulin ... daily dose of insulin ... • Weight-based insulin ... Diabetes #Mellitus #DM2 ... comparison #table #endocrinology
Health risks of obesity

Greatly increased risk (RR >3):
 - Mortality (BMI >30) 
 - Type 2
30) - Type 2 DM ... (BMI of 35 confers ... 92x ^ risk of DM ... Dyslipidaemia - Insulin
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
Dose (TDD) of Insulin ... TDD in units of insulin ... weight in Kg • Insulin ... #pharmacology #endocrinology ... #diabetes #DM2
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
cells, triggering insulin ... Pharmacology #Summary #DM2 ... #diabetes #endocrinology
Gowers' Sign on Physical Exam

Indicative of proximal muscle weakness in muscular dystrophy.

#Gowers #Sign #PhysicalExam #neurology #clinical
Gowers' Sign on ... #Gowers #Sign #PhysicalExam ... muscular #dystrophy #DMD ... #Duchenne
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
• Increases insulin-mediated ... mL/minute/1.73 rm2 ... mL/minute/1.73 m2 ... Pharmacology #Summary #DM2 ... #diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
-> Stimulates Insulin ... will stimulate insulin ... Management #Diabetes #DM2 ... #Endocrinology