1809 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- SLE Anti-histone ... (AMA), Anti-sp100 ... - SLE Anti-SSA ... (Ro), Anti-SSB ( ... - Goodpasture's
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
sclerosis • Anti-Glomerular ... Basement Membrane: Goodpasture's ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... differential #diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Henoch-SchonIein Purpura Anti-GBM ... Limited to Kidney: Anti-GBM ... pulmonary involvement: Anti-GBM ... Disease (Goodpasture's
Main types of autoimmune encephalitis in the ICU. 
Anti-NMDAR anti-N-methyl-d-aspartate receptor, ADEM acute disseminated encephalomyelitis, Anti-GFAP
Anti-NMDAR anti-N-methyl-d-aspartate ... anti-glial fibrillary ... anti-gamma aminobutyric ... anti-leucine-rich ... comparison #table #neurology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... Membrane Disease (Goodpasture's ... @PulmPEEPs #Anti ... Membrane #Disease #Goodpastures ... AntiGBM #diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... membrane: Goodpasture ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... FINDINGS: • AAV or Goodpasture's
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
Hepatitis B Virus Serology ... Interpretation HBsAg - Anti-HBs ... - Anti-HBc - HBeAg ... - Anti-HBe - ... HepatitisB #HBV #Serology
Hepatitis B (HBV) Serology

HBsAg - Presence denotes current HBV infection (chronic or acute)
HBV Core Antibody -
Hepatitis B (HBV) Serology ... some point - Anti-HBcAg ... infection - Anti-HBcAg ... remote infection Anti-HBsAg ... HepatitisB #HBV #Serology
You’ll notice there is an IgM and an IgG core antibody. The presence of IgM anti-HBc
presence of IgM anti-HBc ... IgM anti-HBc is ... presence of IgG anti-HBc ... with HBV, IgG anti-HBc ... Antibody #Levels #Serology
Status Epilepticus - Management
Seizure > 5 mins or two seizures without complete recovery between them
PEDS
Benzo Dose
Benzo Dose 2 → Anti-epileptic ... #2 → Anti-epileptic ... peds #pediatrics #neurology