33 results
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar Basement ... Membrane Disease (Goodpasture's ... the glomerular basement ... membrane and alveolar basement ... Membrane #Disease #Goodpastures
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Anti-Glomerular Basement ... Membrane: Goodpasture's
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... membrane: Goodpasture ... FINDINGS: • AAV or Goodpasture's
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
GBM, glomerular basement
Classic mucosal-dominant Pemphigus Vulgaris. Suprabasal acantholysis leaving behind a “row of tombstones” (i.e. the basal layer
life onto the basement
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
GBM, Glomerular basement
Hemoptysis - Differential Diagnosis Framework
Airways: 
 • Bronchitis
 • Bronchiectasis
 • Malignancy: Primary bronchogenic CA, Endobronchial
Rheumatic/lmmune: Goodpastures
Causes of Hematuria - Glomerular vs Non-glomerular

== Glomerular ==
- Glomerulonephritis 
- Thin basement membrane disease 

==
Glomerulonephritis - Thin basement
A red blood cell (red arrow) is seen crossing the basement membrane (blue arrow) and losing
seen crossing the basement
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Anti-GBM Disease (Goodpasture's