1195 results
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar Basement ... Membrane Disease (Goodpasture's ... the glomerular basement ... membrane and alveolar basement ... Membrane #Disease #Goodpastures
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Anti-Glomerular Basement ... Membrane: Goodpasture's
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... membrane: Goodpasture ... FINDINGS: • AAV or Goodpasture's
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
GBM, glomerular basement
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
GBM, Glomerular basement
Classic mucosal-dominant Pemphigus Vulgaris. Suprabasal acantholysis leaving behind a “row of tombstones” (i.e. the basal layer
life onto the basement
Hemoptysis - Differential Diagnosis Framework
Airways: 
 • Bronchitis
 • Bronchiectasis
 • Malignancy: Primary bronchogenic CA, Endobronchial
Rheumatic/lmmune: Goodpastures
Causes of Hematuria - Glomerular vs Non-glomerular

== Glomerular ==
- Glomerulonephritis 
- Thin basement membrane disease 

==
Glomerulonephritis - Thin basement
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
(Diffuse) Anti-Sm ... disease Anti-GBM - Goodpasture's
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Anti-Glomerular Basement ... staining on IF • No EM