11 results
Comparison of Fever Algorithms for Infants <3 months old

AGE, INCLUSION, TESTS 
REQUIRED, "LOW RISK" CRITERIA, TREATMENT,
Comparison of Fever ... Algorithms for ... of low-risk criteria ... #EBM #Fever ... #Table #Performance
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... nervous system (CNS) dysfunction ... Histopathologic criteria ... MAS #Macrophage #Activation ... Diagnosis #Management #Hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
sequestration and activation ... : ARDS Berlin Criteria ... explain symptoms • Fever ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Diagnosis - Yamaguchi criteria ... 5 of the below criteria ... Minor criteria include ... splenomegaly, liver dysfunction ... AOSD #diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... • Clinical: fever ... , Hb), Hepatic dysfunction ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... genetic immune dysfunction ... following: • Fever ... management #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... , organ dysfunction ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... Diagnosis #Management #Hematology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... Performance thorough ... event, follow ACC algorithm ... with valvular dysfunction ... or LV dysfunction
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... or Neutrophil Dysfunction ... Infection #Fever ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Malignancy (e.g. hematologic ... mild cognitive dysfunction ... to: Arthritis, Fever ... Chronic B-cell activation