13 results
Comparison of Fever Algorithms for Infants <3 months old

AGE, INCLUSION, TESTS 
REQUIRED, "LOW RISK" CRITERIA, TREATMENT,
Comparison of Fever ... Algorithms for ... of low-risk criteria ... #EBM #Fever ... #Table #Performance
Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management 
Source:
Right heart dysfunction ... mechanisms and management ... right ventricular dysfunction ... of myocardial performance ... CongestiveHeartFailure #RVFailure #Criteria
Management Algorithm for Confusion
- Substrate verification, glucose, oxygen checks
- Toxidrome present
- Focal findings on neurologic examination
-
Management Algorithm ... examination - Fever ... , SIRS criteria ... AlteredMentalStatus #Delirium #Management ... #Algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... nervous system (CNS) dysfunction ... Histopathologic criteria ... MAS #Macrophage #Activation ... Syndrome #Diagnosis #Management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Diagnosis - Yamaguchi criteria ... 5 of the below criteria ... Minor criteria include ... splenomegaly, liver dysfunction ... #rheumatology #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... • Clinical: fever ... , Hb), Hepatic dysfunction ... Lymphohistiocytosis #diagnosis #management
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
cytokines, complement activation ... • Symptoms: Fever ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT ... Shock #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... genetic immune dysfunction ... following: • Fever ... Lymphohistiocytosis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... cytopenias and organ dysfunction ... , organ dysfunction ... Diagnostic Criteria ... of 8 HLH-2004 criteria
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... • Excessive activation ... Autonomic Dysfunction ... Diagnostic Criteria ... Myelitis #diagnosis #management