13 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
clinical syndrome associated ... excessive macrophage activation ... genetic immune dysfunction ... • Bicytopenia Treatment ... diagnosis #management #treatment
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... -> microglial activation ... Behavioral • Motor dysfunction ... Treatment: • HAART ... treatment • Cognitive
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... Principles of HIV-Associated ... infections result from reactivation ... Antimicrobial treatment ... Periventricular regions; associated
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Performance thorough ... components: - CV ... event, follow ACC algorithm ... with valvular dysfunction ... or LV dysfunction
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... nervous system (CNS ... ) dysfunction • ... Treatment: • Corticosteroids ... MAS #Macrophage #Activation
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... • Excessive activation ... that results in CNS ... Autonomic Dysfunction ... Transverse Myelitis Treatment
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
and Management Algorithm ... Entacavir, tenofovir vs ... absent the risk of reactivation ... HepatitisB #HBV #Algorithm ... Diagnosis #Management #Treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... involve PNS and CNS ... mild cognitive dysfunction ... Malignancy Associated ... Chronic B-cell activation
Cyclic Vomiting Syndrome (CVS) - Management Algorithm
General Approach:
 - Identify and avoid triggers
 - Good sleep
Vomiting Syndrome (CVS ... ) - Management Algorithm ... use, autonomic dysfunction ... Topiramate and CoQ10 #CVS ... #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... by uncontrolled activation ... Persistent fever, organ dysfunction ... - Associated ... Treatment Approach