4 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... genetic immune dysfunction ... genetic testing for HLH-associated ... • Bicytopenia Treatment ... diagnosis #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... lymphohistiocytosis (HLH ... nervous system (CNS ... ) dysfunction • ... Treatment: • Corticosteroids
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... by uncontrolled activation ... Persistent fever, organ dysfunction ... - Associated ... Treatment Approach
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... -> microglial activation ... Behavioral • Motor dysfunction ... Treatment: • HAART ... treatment • Cognitive