14 results
Guide to systemic mastocytosis

Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
mastocytosis Criteria ... minor or 3 minor criteria ... without organ dysfunction ... hemepath #pathology #algorithm ... #diagnosis #clinical
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... fever syndromes Clinical ... Fever is the main clinical ... nervous system (CNS) dysfunction ... Histopathologic criteria
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... metabolic syndrome criteria ... *Abnormal USS may ... aminotransferase; BMI, body mass ... LFTs #Abnormal #Algorithm
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
Life-threatening organ dysfunction ... cellular/metabolic dysfunction ... cytokines, complement activation ... CLINICAL RECOGNITION ... CLINICAL FEATURES
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... specific) COMMON CLINICAL ... • Essential Criteria ... : Clinical/radiologic ... 2019 ACR/EULAR Criteria
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Life-threatening organ dysfunction ... Clinical construct ... qSOFA, defined as ... AMS (GCS < 15) ... EmmGeezee #Sepsis #Criteria
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... • Excessive activation ... Transverse Myelitis - Clinical ... Autonomic Dysfunction ... Diagnostic Criteria
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Performance thorough ... event, follow ACC algorithm ... or LV dysfunction ... Change in clinical ... stress testing may
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
IDSA Algorithm for ... infection such as ... or those with clinical ... evidence of organ dysfunction ... #SSTIs #Algorithm
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
sympathetic + ADH activation ... Diagnosis (Clinical ... Criteria): • ↑ ... Norepinephrine may ... be substituted as