9 results
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Encapsulated Bacteria Cell ... jirovecii • CNS ... or Neutrophil Dysfunction ... #Causes #Hematology
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... #diagnosis #management ... #differential #causes ... #classification
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thromboembolism (7%) • CNS ... Schistocytes, helmet cells ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... #diagnosis #management ... #differential #causes ... #classification
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... Thyroid (Riedel's), CNS ... complement • Classification ... IGG4 #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... that results in CNS ... Pleocytosis > 100 cells ... • Infectious causes ... Myelitis #diagnosis #management
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
• Endocrine Dysfunction ... marrow: Organ dysfunction ... CNS involvement: ... for endocrine dysfunctions ... Histiocytosis #Diagnosis #Management
Invasive Fungal Infection (IFI)

Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
organ or stem cell ... (most frequent cause ... species (commonly CNS ... include fever, organ dysfunction ... when feasible Management
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM

What Are Demyelinating Diseases?
• Conditions that damage myelin, the protective
nervous system (CNS ... Oligoclonal bands, cell ... - Symptom management ... bladder/bowel dysfunction ... diseases #neurology #CNS