5 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Attempt if high risk ... 500 mg QD until normal ... severe APLS, organ dysfuxtion ... #diagnosis #management
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Performance thorough ... event, follow ACC algorithm ... with valvular dysfunction ... or LV dysfunction ... medical and surgical management
ED Treatment of 
Abnormal Uterine Bleeding 

Hemodynamically unstable 
Resuscitation 
 • ABCs! 
 • Fluids +
Treatment of Abnormal ... packing - increased risk ... Hemodynamically stable ... cancer, liver dysfunction ... Uterine #Bleeding #Management
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Idiopathic LV dysfunction ... Risk Factors and ... thrombus, RV systolic dysfunction ... sx overlap with normal ... Delivery • Stable
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
are usually near-normal ... • Treatment algorithms ... appropriate only for low risk ... patients with no CV risk ... hematology #diagnosis #management