11 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Hb), Hepatic dysfunction ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... Treatment: • ... diagnosis #management #treatment
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
less than 200 cells ... present in 15% of cases ... Antimicrobial treatment ... Demyelinating disease caused ... effect/Edema • EBV
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thromboembolism (7%) • CNS ... Schistocytes, helmet cells ... + Bleeding Treatment ... Treat primary cause ... #treatment #management
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Encapsulated Bacteria Cell ... jirovecii • CNS ... or Neutrophil Dysfunction ... #Causes #Hematology
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
IDSA Algorithm for ... 12 000 or <400 cells ... oral antibiotic treatment ... evidence of organ dysfunction ... including those caused
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... that results in CNS ... Pleocytosis > 100 cells ... Brucellosis - Dengue, EBV ... Transverse Myelitis Treatment
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
recommendations, treatments ... mental, and overall well-being ... combination of dysfunction ... #diagnosis #causes ... Petersen EBM, Skov
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
• Endocrine Dysfunction ... CNS involvement: ... Birbeck granules (EM ... TREATMENT OPTIONS ... with appropriate treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... hyperinflammatory syndrome caused ... Persistent fever, organ dysfunction ... Infections (e.g., EBV ... Treatment Approach
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM

What Are Demyelinating Diseases?
• Conditions that damage myelin, the protective
nervous system (CNS ... Oligoclonal bands, cell ... autoimmune/infectious causes ... bladder/bowel dysfunction ... diseases #neurology #CNS