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differential management rheumatology lupus druginduced hepatology sle antiphospholipid apls biliary cholangitis cirrhosis comparison deficiency dermatology dil disorders eosinophil eosinophilia erythematosus
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Algorithm INDICATIONS ... evaluation or workup ... 1,500 cells/µL Workup ... #Differential #diagnosis ... #hematology #eosinophilia
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... #Deficiency #Testing ... #Algorithm #hematology ... #diagnosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Drug-induced AIHA - Abnormal ... perfringens - Complement-Mediated ... #Algorithm #Causes ... #Hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Idiopathic • Normal ... Complement: IgA ... #differential #diagnosis ... #algorithm #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... - CRP: Usually normal ... • Immunologic Workup ... Positive in 60-80% of cases ... 80% - Low complement
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... Discontinuation of causal ... • Immunologic Workup ... #diagnosis #management
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... Algorithm Pinpoint ... deficiency Work ... #Algorithm #Causes
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... an underlying cause ... Better call hematology ... #Algorithm #workup ... #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... <45% and SF is normal ... elevated, HFE gene testing ... including liver and hematologic
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... Proximal limb muscle wasting ... Differential Diagnosis ... #cholangitis #diagnosis ... #workup #hepatology
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