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diagnosis workup anemia causes hemolytic pancytopenia rheumatology agglutinin cbc cold disease erythematosus extravascular hemolysis immunecompromised immunocompromised infections infectiousdiseases intravascular lupus
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... bartonella (oroya fever ... #workup #hematology ... #testing
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... Diagnosis Algorithm ... perfringens - Complement-Mediated ... #Diagnosis #Algorithm ... #Causes #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... Eating disorders ... Acquired Aplastic Anemia ... #Diagnosis #Algorithm ... #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Positive Coombs testing ... younger pts) Differential ... temperatures by fixing complement ... Symptoms: High fevers ... #hematology #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... especially in the setting ... tachycardia or fever ... #differential # ... neutrophil #WBC #CBC #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup and Differential ... Diagnosis Algorithm ... Eating disorders ... Acquired Aplastic Anemia ... #Hematology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Diagnosis Algorithm ... Periodontal Disease Complement ... Infection #Fever ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... permanent alopecia Differential ... to: Arthritis, Fever ... RNP antibodies, Complement
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
haemophilum • Tropical setting ... Hematologic malignancy ... Presentation: Fever ... Bone Marrow - Anemia ... NTM #Infections #differential
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
include low-grade fevers ... with significant fevers ... • Normocytic anemia ... normal and can help differentiate ... Diagnosis #Management #Rheumatology
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