Granulomas disease infections - GrepMed

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Hepatic and splenic granulomas

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com @febrilepodcast]
#ID #Infectious Diseases

Hepatic and splenic granulomas ... febrilepodcast] #ID #Infectious ... Diseases #Infections ... Microbiology #Micro #granulomas

Causes of Hypercalcemia due to increased Vitamin D levels
• The BIG 3:

Tuberculosis • Fungal Infections ... granulomatous diseases ... vasculitis, Crohn's disease ... pneumonia, Talc granuloma ... Silicone-induced granuloma

Causes of Granulomatous Liver Diseases - Differential Diagnosis
Infections (Bacterial, Viral, Fungal, Parasitic)
Malignancy
Autoimmune
Drugs/Toxins
Others

#Granulomatous #Liver #hepatic #granulomas #Differential

Granulomatous Liver Diseases ... Differential Diagnosis Infections ... Liver #hepatic #granulomas

IBD Mimics
Infectious - Always RULE OUT infection (CMV, C. diff esp.) obtain travel & exposures history:

IBD Mimics Infectious ... Always RULE OUT infection ... : • Granulomas ... intestine: Behcet's disease ... inflammatroy #bowel #disease

Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of

cells to form granulomas ... Chronic kidney disease ... Response: • Granulomas ... Progressive lung disease ... seeding • Caseating granulomas

Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of

cells to form granulomas ... Chronic kidney disease ... Response: • Granulomas ... Progressive lung disease ... seeding • Caseating granulomas

Hansen's Disease (Leprosy)
• Transmission - not completely understood, ?nasal droplets
• Symptoms appear ~5 years

Hansen's Disease ... do not contract disease ... non-caseating granulomas ... x 24 m BIDMC Infectious ... Diseases Fellowship

Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
- DDX:
-

- DDX: - Infection ... - Systemic disease ... to the knee Infectious ... Post-Infectious ... - Eosinophils granuloma

Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and

presentation of the disease ... GPA causes disease ... cell arteritis Infections ... • Fungal infections ... extravascular palisading granulomas

Majocchi’s Granuloma due to Trichophyton rubrum
This is GMS stain and culture of a skin biopsy

Majocchi’s Granuloma ... granulomatous fungal infection ... Fungal infection ... recommended Mayo Clinic Infectious ... Diseases @MayoClinicINFD

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