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diagnosis differential erythematosus signs sle systemic classification management vasculitis behcet centralretinalartery criteria cryofibrinogenemia disease eularacr monoclonal oncology ophthalmology paraproteinemias pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Artery Occlusion ... Pathogenesis and clinical ... anti-coagulation • Hematologic ... Artery Occlusion ... diagnosis #signs #symptoms
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... pericarditis • Hematologic ... hemolysis • Renal ... Erythematosus #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Abdominal pain (20%) Renal ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... pulmonary emboli, and ocular ... thrombi including retinal ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... disease (SVC/IVC occlusion ... Behcet syndrome (Clinical ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Erythematous, macular ... Non-autoimmune rheumatologic ... : • Symptoms limited ... Erythematosus #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Hypergammaglobulinemic macular ... to cold IgG • Lupus ... ↓anion gap • CRAB ... , retinal, DVT, ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... reactions, and vaso-occlusive ... Presentation - Systemic Symptoms ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... reactions, and vaso-occlusive ... Presentation: Systemic Symptoms ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... the most common clinical ... + Nonspecific symptoms ... chondritis • Ocular ... Polychondritis #rheumatology
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