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diagnosis differential erythematosus management sle syndrome classification hematology signs symptoms vasculitis behcet criteria cryofibrinogenemia eularacr monoclonal oncology paraproteinemias sjogrens susac
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Abdominal pain (20%) Renal ... disease (30%): ... symptoms #diagnosis #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Clinical Domains ... hemolysis • Renal ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... association • M > F Clinical ... (SVC/IVC occlusion ... Behcet syndrome (Clinical ... signs #symptoms #rheumatology
Susac Syndrome - Clinical Triad - Central nervous system dysfunction - Branch retinal artery occlusion -
Susac Syndrome - Clinical ... Central nervous system ... artery occlusion ... - Recurrent disease ... Diagnosis #Management #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Erythematous, macular ... Non-autoimmune rheumatologic ... #Diagnosis #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... pulmonary emboli, and ocular ... thrombi including retinal ... and/or venous occlusions ... Diagnosis: • + Clinical
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Others: • Lupus ... Syndrome: - Ocular ... lupus erythematosus ... reactions, and vaso-occlusive ... differential #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... , retinal, DVT, ... Paraproteinemias #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... reactions, and vaso-occlusive ... , and ocular inflammation ... Cogan syndrome: Ocular ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... salivary ducts Clinical ... Central nervous system ... Cytopenia: 2% Systemic ... Sjogrens #Syndrome #Rheumatology
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