91 results
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Proposed Treatment Algorithm ... for MAS / HLH ... #MAS #HLH #Hemophagocytic ... Management #Treatment #Algorithm
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... Auto-amplification loop Diagnosis ... Chediak-Higashi, Griscelli, Purtilo ... #Hemophagocytic ... Lymphohistiocytosis #diagnosis
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Diagnostic Schema ... HLH 2. ... Hyperferritinemia #Algorithm ... #Differential # ... Diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Diagnosis Algorithm ... and Screen for HLH ... HLH syndrome 5. ... • Hypoplastic MDS ... #Diagnosis #Algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Activation Syndrome (MAS ... A subset of hemophagocytic ... lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... Activation #Syndrome #Diagnosis
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Diagnosis Algorithm ... and Screen for HLH ... HLH syndrome 5 ... • Hypoplastic MDS ... #Diagnosis #Algorithm
Differential Diagnosis for Generalized Lymphadenopathy

Viral
• HIV 
• EBV 
• CMV 
• HBV 
• Dengue 
• Rubella
Differential Diagnosis ... Amyloidosis • HLH ... Lymphadenopathy #Differential ... #Diagnosis #Causes ... #Algorithm #Oncology
Chest XRay Nodule / Mass Pattern - Differential Algorithm #Diagnosis #Radiology #Pulmonary #CXR #Nodule #Mass #Pattern
XRay Nodule / Mass ... Pattern - Differential ... Algorithm #Diagnosis ... #CXR #Nodule #Mass ... #Pattern #Differential
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Diagnosis Algorithm ... Alloimmune • anti-HLA ... Thrombocytopenia #Differential ... #Diagnosis #Algorithm
Diagnosis of Primary Amenorrhea
A diagnostic approach to primary amenorrhea. (FSH = follicle-stimulating hormone; LH = luteinizing
Diagnosis of Primary ... Amenorrhea A diagnostic ... follicle-stimulating hormone; LH ... Primary #Amenorrhea #Differential ... #Algorithm