18 results
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
Diagnosis #KSHV #HHV ... lymphoproliferative #KICS
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Clinical Manifestations ... Herpes Viruses (HHV ... herpes virus 6 HHV ... herpes virus 7 HHV ... herpesvirus 8 HHV
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated ... predominance) • Clinical ... Light chain: - HHV8 ... and spleen • Clinical ... de Fremont #HHV8
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
Cytokine Syndrome (KICS ... Diagnosis #KSHV #HHV ... #KICS #Kaposi
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... and uncontrolled HIV ... activity against HHV ... adjunctive therapy #HHV8 ... Treatment #management #opportunistic
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Opportunistic ... : • Most CNS opportunistic ... unsuspected CNS opportunistic ... • CNS opportunistic ... should be based on clinical
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
previously diagnosed opportunistic ... noncompliance • Clinical ... initiation Clinical ... of preexisting opportunistic ... Kaposi sarcoma, HHV8
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
Cytokine Syndrome (KICS ... Definition for KICS ... Requires at least 2 clinical ... 3, and 4. 1) Clinical ... diagnosis #management #hhv8
Acute Otitis Externa (Swimmer’s Ear): Pathogenesis and clinical findings
Pathogens = Pseudomonas aeruginosa (most common opportunistic), Staphylococcus,
Pathogenesis and clinical ... aeruginosa (most common opportunistic ... Immunocompromized (HIV
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Virus (EBV, CMV, HHV8