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diagnosis differential management infections hematology kshv algorithm blood ddx id idfellowcase infectious inflammatory kaposi product reactions rheumatology syndrome acute aki
KSHV Inflammatory Cytokine Syndrome (KICS) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases
KSHV Inflammatory Cytokine ... Syndrome (KICS) ... Diagnosis #KSHV #HHV ... #KICS #Kaposi
Kaposi Sarcoma Herpes Virus (KSHV) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases #Infections #Differential
Diagnosis #KSHV #HHV ... lymphoproliferative #KICS
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory Cytokine ... Syndrome (KICS) ... Working Case Definition ... #Inflammatory #Cytokine ... diagnosis #management #hhv8
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
hypereosinophilia (HE) Caused ... eosinophilopoietic cytokines ... Common causes: ... disease Rare causes ... Viral infections (HIV
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
gut) • Viruses: HSV ... airways) • Viruses: HSV ... reactivation), HHV ... differential #diagnosis #causes
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
pro-inflammatory cytokines ... Virus (EBV, CMV, HHV8 ... Drugs, Unknown cause ... 100 mg/m2) : in case ... emergency, ICU in case
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... Others: • Fat emboli ... • Cholesterol emboli ... • Septic emboli ... • HCV, HBV Not
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... • Drugs • Emboli ... Epithelial cell casts ... • Drugs • HIV ... Diagnosis #Algorithm #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... liver, Thrombosis, Emboli ... • Infectious: HAV ... , HBV, HCV, HEV, ... EBV, HSV, CMV,
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
accumulated inflammatory cytokines ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... 2,000,000,000, HBV
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