31 results
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
IDFellowCase #ID #Infectious ... Diseases #Infections ... Diagnosis #KSHV #HHV ... lymphoproliferative #KICS
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... 20%) congenital infection ... herpes virus 6 HHV ... herpes virus 7 HHV ... Herpes #Viruses #HHV
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
Cytokine Syndrome (KICS ... IDFellowCase #ID #Infectious ... Diseases #Infections ... Diagnosis #KSHV #HHV ... #KICS #Kaposi
Infection-Related Cancers
Viruses:
 • HPV - Cervical, anogenital, head and neck, skin cancer
 • HTLV-1 - Adult
Infection-Related ... Cancers Viruses: • HPV ... T-cell Leukemia • HIV ... carcinoma • HHV ... @drkeithsiau #Infection
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Transplant Infections ... Staphylococci (skin), Gram-negative ... Staphylococci (skin), Gram-negative ... reactivation), HHV ... #Transplant #Infections
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Hepatocellular: Viral infections ... (HAV, HBV, HCV, ... HEV, EBV, CMV), ... biopsy if: • Negative
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Acquired HLH: • Infections ... Virus (EBV, CMV, HHV8 ... Still disease, Infection ... Etiological+++: Anti-infectious
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
carrier state (low HBV ... level) or HBeAg-negative ... replication (high HBV ... less commonly, infection ... #HepatitisB #HBV
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
infection (~1.5% ... probability) and negative ... infection of ~1 ... (~0.5%) and a negative ... infection of ~1
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... and uncontrolled HIV ... activity against HHV ... adjunctive therapy #HHV8 ... opportunistic #infections