9 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... family history - Medications ... plateletcount), peripheral blood ... test, ANA (e.g., SLE ... #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... severe thrombocytopenia ... due to marrow aplasia ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... severe thrombocytopenia ... due to marrow aplasia ... #diagnosis #management ... #hematology #reactions
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Reactions TRALI ... of high parity blood ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Anemia Clinical ... and petechiae Causes ... anemia Treatment ... result from low blood ... Anemia #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... • Severe Liver Disease ... #causes #treatment ... #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... Pure red cell aplasia ... microglobulin Treatment ... workup #oncology #hematology
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... , SLE, trauma, aplastic ... Mucormycosis #Eschar #dermatology ... #skin #clinical ... #photo
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
algorithm 2018. ... median age at diagnosis ... repeated red cell transfusions ... importance of clinical ... #algorithm #hematology