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diagnosis oncology leukemia management chronic lymphocytic differential differentiation hemeonc hodgkins lymphoma mds myelodysplasia myelodysplastic platelets syndrome syndromes thrombocytosis workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... extramedullary disease ... or functional neutropenia ... lymphoid organs When Cancer ... #Leukemia #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... • Reaction to Medications ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... cells can indicate disease ... Cytopenias: • Neutropenia ... microglobulin Treatment ... workup #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... endothelial damage Prophylaxis ... • Steroids: IV ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... PRCA, autoimmune neutropenia ... chemotherapy for low-risk disease ... • Indications ... Leukemia #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... • Neutropenia ... factor (GCSF) treatments ... marrow studies Treatment ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... -95% of cases) Classification ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #hematology #oncology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... algorithm 2018. ... influence outcomes and treatment ... with repeated red cell ... #algorithm #hematology
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