17 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
• Spinal Cord: ... Poliomyelitis, Guillain-Barre ... aminoglycosides) • Muscles: Acid ... #Causes #differential ... #diagnosis #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
, Mild sensory symptoms ... or signs, Cranial ... protein Features Casting ... nervous system signs ... #neurology #neuropathy
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Syndrome ->Cord ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... pulmonary etc) • CNS ... of the spinal cord ... Lack of UMN/LMN signs ... Diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential ... and signs below ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome ... #neurology #differential
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... syphilis, and HIV ... #differential # ... diagnosis #neurology
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... #Tuberculosis #diagnosis ... #differential # ... TB #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... history of cancer, HIV ... ) • Systemic symptoms ... brain lesion • CNS ... #neurology #PHANTOMS
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... (Spinal cord predominant ... • Acute: - IV ... #management #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
(CES) is usually ... • HIV related ... • Guillain-Barre ... lower extremity weakness ... #neurology