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NINDS Diagnostic Criteria for Guillain Barre Syndrome Features Required for Guillain-Barré Syndrome: • Progressive muscle weakness
, Mild sensory symptoms ... or signs, Cranial ... protein Features Casting ... encephalitis spectrum disorders ... #neurology #neuropathy
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal Cord ... Demyelinating Disease (MS ... Poliomyelitis, Guillain-Barre ... Weakness #Causes #differential ... #diagnosis #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Syndrome ->Cord ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... should be based ... Suspect in movement disorders ... in HIV: • CNS ... InfectiousDiseases #Neurology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... (CAS): - Due ... Positive Coombs testing ... Mycoplasma, EBV, HIV ... younger pts) Differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... and signs below ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome ... #diagnosis #neurology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
papilledema • Horner syndrome ... history of cancer, HIV ... ) • Systemic symptoms ... brain lesion • CNS ... #neurology #PHANTOMS
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
pulmonary etc) • CNS ... of the spinal cord ... Lack of UMN/LMN signs ... parainfluenza, Coxsackie, HIV ... #Diagnosis #neurology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
nervous system (CNS ... pachymeningitis • HIV ... • Infiltrating base ... #neurology #noninflammatory ... #differential #
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... The clinical syndrome ... dementia #AIDS #Neurology
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