12 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... Demyelinating syndromes ... ) Blood (75%): Anemia ... #erythematosus # ... signs #symptoms
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... #Lupus #Erythematosus ... autoantibodies #signs ... #symptoms #mimickers
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... photosensitivity, inflammatory ... lupus erythematosus ... : • Symptoms limited ... #Lupus #Erythematosus
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus ... lupus erythematosus ... SLE], AOSD) • Infection ... with leukopenia, anemia ... #Management #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: - Ocular inflammatory ... lupus erythematosus ... Symptoms (Sx) in ... purpura: strong sign ... Cryoglobulins • HIV
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... ischemia • Skin: Erythematous ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... (25-75%): Inflammatory ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... sx + signs/sx of ... vs infection vs ... GCA #Temporal #Signs ... #Management
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
• CT: Halo sign ... papules, pustules, erythematous ... Constitutional symptoms ... 100% of cases), anemia ... #HIV #AIDS #pulmonary
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... • Bilateral signs ... and/or symptoms ... simplex virus, HIV ... - Sjogren - Vasculitis