14 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Demyelinating syndromes ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Gastrointestinal inflammatory ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... : • Nephrotic syndrome ... , HIV) • Glucocorticoid
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
Allergy Pathway for Antibiotic ... rash eosinophilia systemic ... symptoms syndrome ... , Hemolytic anemia ... Prescription #algorithm #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... (25-75%): Inflammatory ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: - Ocular inflammatory ... to exclude are infections ... Symptoms (Sx) in ... purpura: strong sign ... Cryoglobulins • HIV
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... rapidly, and empiric antibiotic
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... • Progressive symptoms ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... sx + signs/sx of ... complaints- anemia ... GCA #Temporal #Signs ... #Management
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... Infections: - ... Inflammatory: ... , Scleroderma, Systemic ... MCTD, Sjogren syndrome